Development of an oxazole conjunctive reagent and application to the total synthesis of siphonazoles.
نویسندگان
چکیده
The preparation of 4-carbethoxy-5-methyl-2-(phenylsulfonyl)methyloxazole and its use in the elaboration of more complex oxazoles are described. A total synthesis of the unique natural products siphonazoles A and B, illustrates an application of this building block. A discussion of the biological activity of the siphonazoles is also presented.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 74 23 شماره
صفحات -
تاریخ انتشار 2009